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Radiological grading of bone tumors based on the reaction of the compact bone and the penetration of the cortex Type (grade) Destruction Contours Compact bone penetra- tion Sclerosis Growth Periosteal reaction Typical examples IA Geographic Sharply-defined No Yes Slow None Enchondroma, non-ossifying bone fibroma, osteoid osteoma IB Geographic Ragged, irregular No, poss. GENETICALLY MODIFIED ORGANISMS Genetic modification of organisms is a very old endeavor. Cannas, Silver coated materials for external fixation devices: in vitro biocompatibility and genotoxicity.

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